Volume 124, Issue 7, Pages (June 2003)

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Volume 124, Issue 7, Pages 1738-1747 (June 2003) Sex-related differences in IBS patients: central processing of visceral stimuli Bruce D Naliboff, Steve Berman, Lin Chang, Stuart W.G Derbyshire, Brandall Suyenobu, Brent A Vogt, Mark Mandelkern, Emeran A Mayer Gastroenterology Volume 124, Issue 7, Pages 1738-1747 (June 2003) DOI: 10.1016/S0016-5085(03)00400-1

Figure 1. Schematic of brain circuits activated by visceral and central nervous system-directed stimuli. Gray highlighted areas indicate brain regions showing greater activation in (A) male patients and (B) female patients. Gastroenterology 2003 124, 1738-1747DOI: (10.1016/S0016-5085(03)00400-1)

Figure 2. Sex-related differences in the response to the gut-directed stimulus. The response to the 45-mm Hg stimulus for the male and female subjects (compared with baseline) is shown. The left column shows voxels of significantly greater activation (P < 0.05) in female patients, and the right column shows voxels with significantly greater activation in male patients (shown in radiologic orientation). Gastroenterology 2003 124, 1738-1747DOI: (10.1016/S0016-5085(03)00400-1)