Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations Miroslava Derenko, Boris Malyarchuk, Tomasz Grzybowski, Galina Denisova, Irina.

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Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations Miroslava Derenko, Boris Malyarchuk, Tomasz Grzybowski, Galina Denisova, Irina Dambueva, Maria Perkova, Choduraa Dorzhu, Faina Luzina, Hong Kyu Lee, Tomas Vanecek, Richard Villems, Ilia Zakharov The American Journal of Human Genetics Volume 81, Issue 5, Pages 1025-1041 (November 2007) DOI: 10.1086/522933 Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 1 Population sample sites, with sample sizes given in parentheses The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 2 PC plot based on haplogroup frequencies for the 18 population samples. Populations are coded as follows: PS = Persians, KU = Kurds, TJ = Tajiks, Ko = Koreans, MN = Mongolians, KM = Kalmyks, BR = Buryats, KN = Khamnigans, TV = Tuvinians, EE = East Evenks, WE = West Evenks, YK = Yakuts, SH = Shors, KH = Khakassians, AL = Altaians-Kizhi, TL = Teleuts, TG = Telenghits, and CH = Chukchi. The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 3 The phylogenetic tree of complete mtDNA sequences of haplogroups N1, X2e, and J1b. The tree is rooted in haplogroup N. Mutations are scored relative to the rCRS.39 The information of the reported samples is presented in table 1. Seven additional complete sequences were taken from the literature,22,26,48,49 and particular sequences from these articles are referred to as CH, MP, MR, and NMM, respectively, followed by a number sign (#) and the original sample code. For subhaplogroups I1, I2, and I3, only diagnostic mutations are shown, according to the classification.20,26,28 For sample CH#230,22 only coding-region information is available. Mutations are shown on the branches and are transitions unless the base change is explicitly indicated. Deletions are indicated by a “D” after the deleted nucleotide position. Underlined nucleotide positions occur at least twice in the tree. The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 4 Phylogenetic tree of complete mtDNA sequences of haplogroups A and Y. The tree is rooted in haplogroup N. The tree includes 36 mtDNAs, of which 31 are novel and 5 were reported elsewhere.14,19,27 Insertions are indicated by a dot followed by the number and type of inserted nucleotide(s). For additional information, see the figure 3 legend. The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 5 Phylogenetic tree of complete mtDNA sequences of haplogroups C1, G1, and D4. The tree is rooted in haplogroup M. For subhaplogroup D2b, only diagnostic mutations for specific lineages are indicated, according to data reported elsewhere.9 D2 and D2b coalescence-time estimates were obtained with consideration of the whole diversity within D2b subclusters. For additional information, see the figure 3 legend. The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 6 Phylogenetic tree of complete mtDNA sequences of haplogroup M7. The tree is rooted in haplogroup M. For additional information, see the figure 3 legend. The American Journal of Human Genetics 2007 81, 1025-1041DOI: (10.1086/522933) Copyright © 2007 The American Society of Human Genetics Terms and Conditions