Sensitivity, specificity, positive predictive value, and negative predictive value for the different cutoffs used. Sensitivity, specificity, positive predictive.

Slides:



Advertisements
Similar presentations
To evaluate sensitivity, each of the 76 specimens (38 serum pairs) were tested using three serology tests. All testing was performed at the university.
Advertisements

The disease and Panbio product training Q fever. Overview “Query” fever First described in Australia World wide zoonosis Caused by the bacterium Coxiella.
Pathogenic Microbiology
Cat Scratch Disease.
Bacterial Infection of Cardiovascular system By Dr. Humodi A. Saeed Associate Prof. of Medical Microbiology College of Medical Laboratory Science Sudan.
Case of Sick Student Fever 105 Swollen throat glands Sore throat Based on throat seems to be bacterial.
Holland Laboratory David A. Leiby, PhD Transmissible Diseases Department American Red Cross Holland Laboratory and Department of Microbiology and Tropical.
Hypothetical distribution of test results for healthy and diseased individuals. The position of the "cutoff point" between "normal" and "abnormal" (or.
How do we judge efficacy of a screening test?
16S rRNA gene abundance and total gene expression of Tannerella species in healthy patient and periodontitis patient samples. 16S rRNA gene abundance and.
Involvement of matrix metalloproteinases in chronic Q fever
Figure 1. Table for calculating the accuracy of a diagnostic test.
Autoradiographs of cDNA gene array of regulatory genes from untreated control (column A) and quercetin-treated (column B) cells. Autoradiographs of cDNA.
Effect of quercetin on colony-forming abilities of prostate cancer cell lines with different aggressive potentials. Effect of quercetin on colony-forming.
The K594ScFv-SEA-D227A fusion protein targets CTL to lyse EA
Effect of OPN on apoptosis of DCs
Ex vivo IL-6 production. Ex vivo IL-6 production. Human whole blood was stimulated with the indicated doses of the E. coli O113 endotoxin that was used.
Proinflammatory activities of Lactobacillus subcellular fractions.
Flow cytometry analysis of TNF-β- and IL-10-producing CD33+ cells.
Signal transduction induced by Lactobacillus spp.
Hematological alterations after endotoxin injection.
Tetramer staining performed to determine frequencies of epitope-specific T cells after clearance of HPV16 infection but prior to isolation of T-cell clones.
Western blot results for serum samples obtained from experimentally vaccinated dogs prior to and at various times (weeks) following initial vaccination.
Kinetics of CXC chemokine appearance after endotoxin injection.
Profiles of anti-inflammatory cytokines after endotoxin injection.
Effect of route of administration (i.v. versus i.p.).
Effects of E. coli and S. aureus infection on levels of TNF-α and IL-1β in milk. Effects of E. coli and S. aureus infection on levels of TNF-α and IL-1β.
Multiplexed whole bacterial antigen microarray, a new format for the automation of serodiagnosis: the culture-negative endocarditis paradigm  F. Gouriet,
(A) CDK2 and p53 gene expression levels, as quantitated by real-time quantitative PCR with SYBR Green master mix (Stratagene, La Jolla, Calif.). (A) CDK2.
Predicted number of joint bleeds according to factor activity level and age group for patients with hemophilia A or B based on a regression model. Predicted.
PCR amplification of the ORF encoding the cytosolic p36 protein of M
Percentage of patients with type 2 diabetes with A1C < 7% (n = 248), blood pressure > 130/80 mmHg (n = 248), and LDL cholesterol < 100 mg/dl (n = 207)
Contribution of individual serovars within serogroups isolated in the United States in Contribution of individual serovars within serogroups isolated.
Plasma levels of GLP-1 are increased in patients with critical illness and correlate with disease severity. Plasma levels of GLP-1 are increased in patients.
Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value, Area Under the Curve, and 95% CIs for the 0, 10, 25, 50, and 100 SatSeconds.
Phylogenetic network with concatenated 16S rRNA, 23S rRNA, groEL, rpoB, and dnaK sequences (3,009 unambiguously aligned base pairs), including 71 Coxiella-like.
Table 1. Diagnostic methods for systemic fungal infection (n=70)
Growth of B. dermatitidis yeast is inhibited by deferoxamine only at concentrations of 0.5 mM or greater. Growth of B. dermatitidis yeast is inhibited.
Shell vial system protocols used for specific isolation of Bartonella, Coxiella burnetii, rickettsiae, or T. whipplei and for unspecific research into.
IL-6 production with increasing doses of endotoxin.
Intracellular TNF-α and IL-4 expression in gated CD33+ monocytes by three-color flow cytometry. Intracellular TNF-α and IL-4 expression in gated CD33+
The NTP increases tyrosine phosphorylation of PLC-γ1.
Schematic representation of the reactivities of IgM antibodies induced against Gly-Ala repeats of EBNA-1 and against glycine-rich motifs of HCMV antigens,
Scattergrams showing IgG- and IgA-specific OD490 values measured with the Campylobacter-specific P18/P39 ELISA in sera from healthy controls and from GBS.
Comparison of OPN production by mature DCs and activated macrophages.
OPN mediates maturation from immature DCs to mature DCs
Diagnostic testing for identification of the microbiological etiology of infective endocarditis. Diagnostic testing for identification of the microbiological.
Reactivity of the anti-p36 MAbs against whole M
NK activity in healthy donors (n=51) and patients with FRH upon recurrence (n=28) and remission (n=23). NK activity in healthy donors (n=51) and patients.
Effects of intramammary infection with E. coli or S
Flow cytometry analysis of intracellular cytokine expression in control PBMC (left set of panels) and following either PMA-ionomycin activation (middle.
Representative cytokine and cytotoxicity responses to CMV peptides on day 0 and day 7 in one HLA A2+ donor. Representative cytokine and cytotoxicity responses.
Eight weeks after primary i. n
Effect of HL60 cell age (expressed in cell passage) on opsonophagocytic activity. Effect of HL60 cell age (expressed in cell passage) on opsonophagocytic.
Relation between the total white blood count and the absolute lymphocyte count prior to the first vaccination and the response to vaccination. Relation.
IgM-specific immunoblot analysis of different HCMV recombinant antigens with a selected serum sample from an HCMV-seronegative patient with acute EBV-induced.
Microcolonies of S. pneumoniae serotype 6B on a Todd-Hewitt agar-yeast extract plate with an overlay containing TTC and antibiotic after 18 h of incubation.
Dot plot comparison of EBNA-1 with recombinant antigens 52/3 (aa 297 to 433 of pUL44) and UL57/3 (aa 545 to 601 of pUL57) of HCMV, containing glycine-rich.
Effects of intramammary infection with E. coli or S
Flow cytometric gating strategy used to identify CD69 surface expression on CD4 (left paired columns) and CD8 (right paired columns) T lymphocytes. Flow.
Distributions of levels of antibodies to periodontal pathogens and plasma vitamin C concentrations. Distributions of levels of antibodies to periodontal.
Anti-PT IgG results from 227 patients with coughs of unknown etiology who reported the severity of cough on a scale from 0 to 10. Anti-PT IgG results from.
Quantitation of apoptosis in M. aviumsubsp
Immunoblot of scFv antibody detected with an anti-FLAG antibody.
OPN production by immature DCs and mature DCs treated with PAMPs
Mean reciprocal IFA titer results for serum samples from experimentally vaccinated animals. Mean reciprocal IFA titer results for serum samples from experimentally.
Amino acid sequence of antigenic fragments 52/3 and UL57/3 of pUL44 and pUL57, respectively, and sequence comparison by dot plot analysis. Amino acid sequence.
The NTP inhibits the AFC response to SRBC
Indirect immunofluorescence reactions on primate smooth muscle tissue for EMA detection depicting the following: (A) prozone reactions at low dilution.
Surface CD4 and CD14 and intracellular TNF-α expression in PBMCs
Presentation transcript:

Sensitivity, specificity, positive predictive value, and negative predictive value for the different cutoffs used. Sensitivity, specificity, positive predictive value, and negative predictive value for the different cutoffs used. The positive group represents patients with endocarditis due to either C. burnetii (n = 30) or Bartonella sp. (n = 20). The negative group comprises 40 apparently healthy blood donors, 99 patients with blood culture-positive endocarditis of known etiology, 15 patients with cat scratch disease, 15 patients with acute Q fever, and 25 patients seropositive for bacterial or viral diseases not related to Bartonella or Coxiella species. J. M. Rolain et al. Clin. Diagn. Lab. Immunol. 2003; doi:10.1128/CDLI.10.6.1147-1148.2003