Motor coordination is enhanced by genetic deletion of Best1 or MAOB but impaired by overexpression of MAOB. (A) Experimental timeline and schematic illustration.

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Motor coordination is enhanced by genetic deletion of Best1 or MAOB but impaired by overexpression of MAOB. (A) Experimental timeline and schematic illustration for rotarod test. Motor coordination is enhanced by genetic deletion of Best1 or MAOB but impaired by overexpression of MAOB. (A) Experimental timeline and schematic illustration for rotarod test. (B) Experimental timeline for selegiline treatment and rotarod test. (C–F) Summary graph showing latency to fall during test sessions. Error bars are SEM; *P < 0.05; **P < 0.01; ns indicates P > 0.05. Ctrl, control; Sele., selegiline. Junsung Woo et al. PNAS 2018;115:19:5004-5009 ©2018 by National Academy of Sciences