Volume 124, Issue 1, Pages (January 2003)

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Presentation transcript:

Volume 124, Issue 1, Pages 270-271 (January 2003) WNT-inducible signaling pathway protein 3, WISP-3, is mutated in microsatellite unstable gastrointestinal carcinomas but not in endometrial carcinomas Lin Thorstensen, Ruth Holm, Ragnhild A. Lothe, Claes Tropé, Beatriz Carvalho, Manuel Sobrinho-Simoes, Raquel Seruca Gastroenterology Volume 124, Issue 1, Pages 270-271 (January 2003) DOI: 10.1053/gast.2003.50034 Copyright © 2003 American Gastroenterological Association Terms and Conditions

Fig. 1 (A) Frequency of frame-shift mutations in the WISP-3 gene in MSI colorectal, gastric, and endometrial carcinomas. (B) One MSI gastric carcinoma with wild-type (wt) WISP-3 (tumor 16) and one with 1 base pair deletion (del) within the (A)9 repeat of WISP-3 (tumor 103). The tumors were analyzed with PCR followed by separation of the products by capillary electrophoresis on an ABI PRISM 310 Genetic Analyser. Gastroenterology 2003 124, 270-271DOI: (10.1053/gast.2003.50034) Copyright © 2003 American Gastroenterological Association Terms and Conditions