Making the Most of In Vitro Tests to Diagnose Food Allergy

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Presentation transcript:

Making the Most of In Vitro Tests to Diagnose Food Allergy Alexandra F. Santos, MD, PhD, Helen A. Brough, MBBS, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 5, Issue 2, Pages 237-248 (March 2017) DOI: 10.1016/j.jaip.2016.12.003 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Tests used to diagnose IgE-mediated food allergy reflect different aspects of the underlying mechanism of this immune-mediated disorder: the skin prick test measures the response of skin mast cells to allergen, the basophil activation test measures the response of circulating basophils to allergen, and IgE tests measure the concentration of circulating IgE, either total IgE or sIgE to allergen extracts or to individual allergen components. Total IgE and allergen-specific IgG4 can be used to calculate ratios with allergen sIgE. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 237-248DOI: (10.1016/j.jaip.2016.12.003) Copyright © 2017 The Authors Terms and Conditions