Lotte Bruens, Hugo J.G. Snippert Cell Stem Cell

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Presentation transcript:

Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells Lotte Bruens, Hugo J.G. Snippert Cell Stem Cell Volume 21, Issue 1, Pages 3-5 (July 2017) DOI: 10.1016/j.stem.2017.06.001 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Manipulating the Lineage Commitment of Pluripotent Stem Cells into Different Gastrointestinal Organoids Previously, the Wells lab has shown how gastric (top row) and small intestinal organoids (middle row) can be derived from pluripotent stem cells (PSCs). Múnera et al. (2017) describe how colon organoids can be established by the induction of BMP signaling (dashed box). All three organoid types mature upon transplantation into the kidney capsule. Cell Stem Cell 2017 21, 3-5DOI: (10.1016/j.stem.2017.06.001) Copyright © 2017 Elsevier Inc. Terms and Conditions