Nat. Rev. Neurol. doi: /nrneurol

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Nat. Rev. Neurol. doi:10/1038/nrneurol

Nat. Rev. Neurol. doi: /nrneurol

MRI findings in MS. A. Axial first-echo image from T2-weighted sequence demonstrates multiple bright signal abnormalities in white matter, typical for.

MRI and possible differentiating features with nonconventional MRI

Figure 1 Perivenous distribution of multiple sclerosis lesions

Figure 2. MRI features of patients with MS who had antibodies to myelin oligodendrocyte glycoprotein MRI features of patients with MS who had antibodies.

Figure 4 Paradoxical immune reconstitution inflammatory syndrome

Nat. Rev. Neurol. doi: /nrneurol

Figure 1 Initial brain imaging (A–C) patient 1; (D–F) patient 2; (G–I) patient 3; (J–L) patient 4; and (M) patient 2. Initial brain imaging (A–C) patient.

Nat. Rev. Neurol. doi: /nrneurol

Nat. Rev. Neurol. doi: /nrneurol

Example of MRIs of a lacune from a haemorrhagic source (A,B), and from a lacunar infarct (C, D). Example of MRIs of a lacune from a haemorrhagic source.

Figure 3 3D magnetic resonance neurography

Nat. Rev. Neurol. doi: /nrneurol

Volume 78, Pages (January 2018)

Figure 4 Neuromyelitis optica spectrum disorder brain lesions

Figure 1 Brain MRI findings in the present case

STRIVE, STandards for Reporting and Imaging of Small Vessel Disease: example findings (upper), schematic representation (middle) and a summary of imaging.

Figure 3 Associations of [11C](R)-PK11195 binding to disability and diffusion tensor imaging (DTI) changes in patients with MS Associations of [11C](R)-PK11195.

Figure 4. Brain imaging and neuropathologic demonstration of Epstein-Barr virus (EBV) encephalitis in patient PT-10 Brain imaging and neuropathologic demonstration.

Vincentius J. A. Verlinden, MSc, Jos N

A b c d Figure 1: Strong T2 weighted images (inversion recovery sequences with fat suppression, TIRM) of a 18 year-old girl document a significant reduction.

Figure 2 Evolution of MRI abnormalities in faciobrachial dystonic seizures Axial fluid- attenuated inversion recovery (FLAIR)-weighted images from patient.

Figure 2 Orbital MRI findings One-third of myelin oligodendrocyte glycoprotein antibody–positive patients revealed extensive enhancement patterns that.

Figure 1 Coronal MRI images showing the evolution of white matter abnormality and atrophy of patient 1 Coronal MRI images showing the evolution of white.

Figure Facial photograph during headache attack and brain and upper cervical cord MRI Facial photograph during headache attack and brain and upper cervical.

Nat. Rev. Neurol. doi: /nrneurol

Figure 3 Example of venous narrowing

Typical manifestation of white matter change on MRI fluid-attenuated inversion recovery imaging in a 37-year-old female patient with chronic migraine.

Figure 2 Examples of lesions with and without central veins

Figure 1 Evolution of multiple sclerosis

Nat. Rev. Neurol. doi: /nrneurol

Figure 1 MRI head in faciobrachial dystonic seizures (A) Axial fluid-attenuated inversion recovery image from patient 3 in table 2 shows T2-weighted hyperintensity.

Case 1, a 45-year-old female (same patient shown in Figure 1 images) with recurrent infarctions in the right middle cerebral artery. (A) Axial fluid attenuation.

Figure 1. Prebiopsy and postbiopsy MRI

Figure 3 MRI findings in opportunistic infections of the CNS

Figure 4 11C-PK11195-PET scans showing the evolution of neuroinflammation in a patient after stroke Figure 4 | 11C-PK11195-PET scans showing the evolution.

Nat. Rev. Neurol. doi: /nrneurol

Long-term appearances of lacunar infarcts (arrows: old stroke lesion on the follow-up scans). Long-term appearances of lacunar infarcts (arrows: old stroke.

Figure 2 T2-weighted and subtraction images

Figure 2 Exemplary MRI of a patient with contrast enhancement on postcontrast FLAIR MRI of a 54-year-old patient with viral meningitis caused by varicella-zoster.

Figure 2 7T MRI can differentiate between early PML and MS lesions Two different patterns of brain lesions were observed using 7T MRI: ring-enhancing lesions.

Figure MRI and neuropathologic characteristics of the tumefactive demyelinating lesion in our patient MRI and neuropathologic characteristics of the tumefactive.

STRIVE, STandards for Reporting and Imaging of Small Vessel Disease: example findings (upper), schematic representation (middle) and a summary of imaging.

Figure 2 DTI values between the hepatitis C group and controls(A) DTI FA values, (B) DTI diffusion values. *Statistically significant at FDR-adjusted p.

In 507 follow-up images, only 1

Example of MRIs of a lacune from a haemorrhagic source (A,B), and from a lacunar infarct (C, D). Example of MRIs of a lacune from a haemorrhagic source.

Figure 2 Example of venous narrowing

Nat. Rev. Neurol. doi: /nrneurol

Examples of typical clinical MRI. (A).

Figure 2 Cerebral and spinal MRI (A) Restricted diffusion of both optic nerves (arrows) on diffusion-weighted and apparent diffusion coefficient imaging.

Figure Genetic deletion and MRI changes with EHMT1 deletion

Nat. Rev. Neurol. doi: /nrneurol

Anatoly Shuster, MD, Mehran Midia, MD

Figure 1 Reibergram (CSF/serum quotient diagram) of all included patients Increasing albumin quotients reflect increasing blood-brain barrier dysfunction.

Figure 1 Brain MRI Brain MRI (A) Axial fluid-attenuated inversion-recovery images show perilesional edema in both cerebellar hemisphere and hypointense.

Typical manifestation of white matter change on MRI fluid-attenuated inversion recovery imaging in a 37-year-old female patient with chronic migraine.

Figure 1 Detailed overview of treatment course and paraclinical findings Maximum intensity projection maps of supratentorial inversion recovery images.

Fig. 4 DMI visualizes the Warburg effect in a patient with GBM after oral [6,6′-2H2]glucose intake. DMI visualizes the Warburg effect in a patient with.

Figure 2 Characteristic MRI features of adult leukodystrophies

Figure Rapid progression of lesions after natalizumab treatment(A) MRI from February Rapid progression of lesions after natalizumab treatment(A)

Long-term appearances of lacunar infarcts (arrows: old stroke lesion on the follow-up scans). Long-term appearances of lacunar infarcts (arrows: old stroke.

Fig day-old female with hypoglycemic encephalopathy

Figure 3 Patient 2 MRI evolution over time before relapse

Figure 2 Patient 1 MRI evolution over time

Figure 1 MRI at presentation The axial diffusion-weighted image (A) showed restricted diffusion throughout the cortical ribbon of the right hemisphere.

T2 shinethrough artifact in DWI

Axial magnetic resonance imaging (MRI) of a 30 year old man with relapsing remitting multiple sclerosis (MS) showing multiple periventricular lesions:

A. A. Computed tomographic (CT) scan, epidural hematoma, B. CT scan, subdural hematoma. C. CT scan, subarachnoid hemorrhage. D. Magnetic resonance image.

Presentation transcript:

Nat. Rev. Neurol. doi:10.1038/nrneurol.2015.194 Figure 1 Illustration of tissue and lesion appearance on conventional and nonconventional MRI Figure 1 | Illustration of tissue and lesion appearance on conventional and nonconventional MRI. In a young female patient with RRMS, a | T2-FLAIR MRI reveals macroscopic acute (thick arrow) and chronic (thin arrows) MS lesions with high sensitivity; however, b | postcontrast T1-weighted images are needed to identify the ring-enhancement that is typical of acute lesions owing to the breakdown of the blood–brain barrier. c | Microstructural tissue changes can be quantified with MTI, which shows a reduction of the magnetization transfer ratio at the site of the active lesion. Note the different appearance of the lesion on each of these three maps. DTI reveals d | reduced fractional anisotropy and e | increased mean diffusivity in this patient. f | SWI can be used to assess regional iron accumulation, and highlights the venous structures seen in relation to MS lesions. Abbreviations: DTI, diffusion tensor imaging; FLAIR, fluid-attenuated inversion recovery; MS, multiple sclerosis; MTI, magnetization transfer imaging; RRMS, relapsing–remitting MS; SWI, susceptibility-weighted imaging. Enzinger, C. et al. (2015) Nonconventional MRI and microstructural cerebral changes in multiple sclerosis Nat. Rev. Neurol. doi:10.1038/nrneurol.2015.194