Recombinant Human C1-Esterase Inhibitor to Treat Acute Hereditary Angioedema Attacks in Adolescents James W. Baker, MD, Avner Reshef, MD, Dumitru Moldovan,

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Presentation transcript:

Recombinant Human C1-Esterase Inhibitor to Treat Acute Hereditary Angioedema Attacks in Adolescents James W. Baker, MD, Avner Reshef, MD, Dumitru Moldovan, MD, PhD, Joseph R. Harper, PharmD, Anurag Relan, MD, Marc A. Riedl, MD, MS The Journal of Allergy and Clinical Immunology: In Practice Volume 5, Issue 4, Pages 1091-1097 (July 2017) DOI: 10.1016/j.jaip.2016.11.005 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Median time to beginning of symptom relief with persistence (A) and median time to minimal symptoms (B), by number of HAE attacks. ∗One HAE attack (attack 1) was excluded because overall VAS score was not available in 1 patient. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1091-1097DOI: (10.1016/j.jaip.2016.11.005) Copyright © 2017 The Authors Terms and Conditions

Figure 2 Kaplan-Meier plot of the time to beginning of relief of symptoms with persistence (A) and minimal symptoms (B), measured using the overall VAS score. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1091-1097DOI: (10.1016/j.jaip.2016.11.005) Copyright © 2017 The Authors Terms and Conditions

Figure 3 Mean functional C1-INH (A) and antigenic C1-INH (μg/mL) (B) over time for all attacks. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1091-1097DOI: (10.1016/j.jaip.2016.11.005) Copyright © 2017 The Authors Terms and Conditions