Genetic Linkage of the Muckle-Wells Syndrome to Chromosome 1q44

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Presentation transcript:

Genetic Linkage of the Muckle-Wells Syndrome to Chromosome 1q44 Laurence Cuisset, Joost P.H. Drenth, Jean-Marie Berthelot, Alain Meyrier, Gérard Vaudour, Richard A. Watts, David G.I. Scott, Anne Nicholls, Sylvana Pavek, Christian Vasseur, Jacques S. Beckmann, Marc Delpech, Gilles Grateau The American Journal of Human Genetics Volume 65, Issue 4, Pages 1054-1059 (October 1999) DOI: 10.1086/302589 Copyright © 1999 The American Society of Human Genetics Terms and Conditions

Figure 1 Pedigree of the three families with haplotype analysis in the region of linkage on chromosome 1. Affected individuals are shown as blackened circles (females) or blackened squares (males). Deceased individuals are denoted by diagonal slashes. The American Journal of Human Genetics 1999 65, 1054-1059DOI: (10.1086/302589) Copyright © 1999 The American Society of Human Genetics Terms and Conditions

Figure 2 Multipoint linkage analysis between MWS and selected markers on chromosome 1q. D1S2811 was arbitrarily assigned position 0, and the order and genetic distances of the maker loci were determined by the use of the Généthon genetic map (Dib et al. 1996). The American Journal of Human Genetics 1999 65, 1054-1059DOI: (10.1086/302589) Copyright © 1999 The American Society of Human Genetics Terms and Conditions