Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous.

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Presentation transcript:

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes by Rodrigo Martino, Marı́a Dolores Caballero, José Antonio Pérez Simón, Carmen Canals, Carlos Solano, Alvaro Urbano-Ispı́zua, Joan Bargay, Angel Léon, Josep Sarrá, Guillermo F. Sanz, José Marı́a Moraleda, Salut Brunet, Jesús San Miguel, and Jorge Sierra Blood Volume 100(6):2243-2245 September 15, 2002 ©2002 by American Society of Hematology

Disease progression after PBSCT Disease progression after PBSCT.Cumulative incidence of disease progression after allogeneic PBSCT with RIC in patients with (n = 24) and without (n = 13) GVHD (acute grade II-IV or chronic GVHD). Disease progression after PBSCT.Cumulative incidence of disease progression after allogeneic PBSCT with RIC in patients with (n = 24) and without (n = 13) GVHD (acute grade II-IV or chronic GVHD). The 1-year incidence of disease progression in patients with and without GVHD was 13% (95% CI, 4%-34%) and 58% (95% CI, 36%-96%), respectively (P = .008). Rodrigo Martino et al. Blood 2002;100:2243-2245 ©2002 by American Society of Hematology