(A) Vascular endothelial growth factor D (VEGF-D) staining in luminal ductal cells with occasional staining in myoepithelial cells of normal breast. (A)

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Presentation transcript:

(A) Vascular endothelial growth factor D (VEGF-D) staining in luminal ductal cells with occasional staining in myoepithelial cells of normal breast. (A) Vascular endothelial growth factor D (VEGF-D) staining in luminal ductal cells with occasional staining in myoepithelial cells of normal breast. (B) Expression in areas of cystic disease, with enhanced VEGF-D expression in duct epithelial cells (inset: nerve and stromal cells that are also immunopositive). (C) Heterogeneous staining of VEGF-D in malignant epithelium in a poorly differentiated tumour and (D) a well differentiated tumour with granular staining at the apical pole of glands. (E) Enhanced VEGF-D immunostaining at the periphery of a tumour (arrows) without upregulation in an adjacent area of necrosis (asterisk). (F) Strong staining for VEGF-D in a lymphatic tumour embolus. M J Currie et al. J Clin Pathol 2004;57:829-834 Copyright © by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.