Cellular reproduction & cancer

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Presentation transcript:

Cellular reproduction & cancer Chapters 17 & 18

Mitosis a type of cell division for asexual reproduction

DNA replication-the big picture

After DNA replication. . . sister chromatids cytokinesis

Cytokinesis in animal cells

Sexual reproduction

Meiosis

Meiosis big picture: two cell divisions

During meiosis I

Crossing over

After crossing over. . .

Influences on cell division Chemical factors Physical factors

Chemical factors Growth factors;

Physical factors Density-dependent inhibition Anchorage dependence

Death is part of a cell life cycle

What happens when the cell cycle malfunctions?

Cancer cells are rounder / larger Cancerous leukemia cells (L) & normal marrow cells (R)

Cancer cells produce their own signals to divide

Cancer cells do not display density-dependent inhibition

Cancer cells do not display anchorage dependence

Cancer cells can stimulate the development of blood vessels

Cancer cells are essentially immortal HeLa cells, 1951