Mitosis: New Roles for Myosin-X and Actin at the Spindle

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Mitosis: New Roles for Myosin-X and Actin at the Spindle Martin Wühr, Timothy J. Mitchison, Christine M. Field  Current Biology  Volume 18, Issue 19, Pages R912-R914 (October 2008) DOI: 10.1016/j.cub.2008.08.043 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Model of the domain structures of myosin-X and their functional associations [10]. Current Biology 2008 18, R912-R914DOI: (10.1016/j.cub.2008.08.043) Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 2 Model by Woolner et al. [9] for myosin-X's involvement in spindle-length regulation. Interaction of astral microtubules and cortical F-actin stretch the spindle while microtubule-bound myosin-X pulls on spindle-associated F-actin thereby shortening it. Current Biology 2008 18, R912-R914DOI: (10.1016/j.cub.2008.08.043) Copyright © 2008 Elsevier Ltd Terms and Conditions