From Gene to Protein.

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Presentation transcript:

From Gene to Protein

Central Dogma of Biology

Promoter Region

Coding (sense) and Noncoding (antisense) strands of DNA: The CODING strand contains the gene- most genes start with ATG The NONCODING strand gets TRANSCRIBED! This is referred to as the TEMPLATE strand. WHY???

Initiation and Termination Sites on DNA: Initiator Sequence: TAC Terminator Sequence: ATT, ATC or ACT

Transcription: Initiation

Transcription: Elongation

Transcription: Termination

Pre mRNA and mature mRNA

Post-transcriptional Modifications: 5’ Cap

Post-transcriptional Modifications: 3’ Poly A Tail

Post-transcriptional Modifications: Splicing

Why is Splicing Important?