Mitochondrial import machinery: TOM - the translocase of

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Presentation transcript:

Mitochondrial import machinery: TOM - the translocase of the outer membrane

Tom40 - the major translocation channel

The Tim23 complex - the major translocation channel in the inner mitochondrial membrane

Transclocation across the inner mitochondrial membrane

Insertion of outer membrane proteins via TOB/SAM

Sorting pathways to the inner mitochondrial membrane

Sorting pathways to the intermembrane space

Mitochondria are highly dynamic and undergo constant fusion and fission cycles

Mitochondria are highly dynamic Fzo1 Mgm1 Ugo1 Dnm1

Mitochondrial fission and fusion machineries relies on multiple GTPases With Ugo1 /fusion