Survival outcomes and interval between lymphoscintigraphy and SLNB in cutaneous melanoma- findings of a large prospective cohort study Fionnuala M. O'Leary,

Slides:

Advertisements

Similar presentations

How surgeons can find information online? Martin Hewitt International Journal of Surgery Volume 5, Issue 6, Pages (December 2007) DOI: /j.ijsu

Advertisements

Nicoletta Colombo, Martin Gore

Treatment of stage I NSCLC in elderly patients: A population-based matched-pair comparison of stereotactic radiotherapy versus surgery David Palma, Otto.

Treatment of Primary Varicose Veins by Endovenous Obliteration with the VNUS Closure System: Results of a Prospective Multicentre Study Ph. Nicolini,

The progressive nature of peripheral arterial disease in young adults: A prospective analysis of white men referred to a vascular surgery service R.James.

The effect of perioperative chemotherapy for patients with an adenocarcinoma of the gastroesophageal junction: A propensity score matched analysis K.

Axillary-to-carotid artery bypass grafting for symptomatic severe common carotid artery occlusive disease Joseph P. Archie, PhD, MD Journal of Vascular.

Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.

Elizabeth A. David, MD, David T

Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.

Outcome of Ultrasound-guided Sclerotherapy for Varicose Veins: Medium-term Results Assessed by Ultrasound Surveillance K.A. Myers, D. Jolley, A. Clough,

Transanal total mesorectal excision (TaTME) for rectal cancer: Step by step description of the surgical technique for a two-teams approach M.C. Arroyave,

Log odds of positive lymph nodes is a superior prognostic indicator in stage III rectal cancer patients: A retrospective analysis of 17,632 patients in.

International Journal of Surgery

Volume 145, Issue 2, Pages (May 2017)

Nirav S. Kapadia, MD, MS, Luca F. Valle, MD, Julie A

Open surgery for atherosclerotic chronic mesenteric ischemia

Selma Masic, Janet E. Cowan, Samuel L. Washington, Hao G

Susan C. Scott, MD, Nathan A. Pennell, MD, PhD

Surgical treatment is decisive for outcome in chondrosarcoma of the chest wall: A population-based Scandinavian Sarcoma Group study of 106 patients Björn.

Outcome and predictors of treatment failure in early post-surgical prosthetic joint infections due to Staphylococcus aureus treated with debridement

Salvage Lung Resection After Definitive Radiation (>59 Gy) for Non-Small Cell Lung Cancer: Surgical and Oncologic Outcomes Julie E. Bauman, MD, Michael.

Comparison of two treatment regimens for eradication of Pseudomonas aeruginosa infection in children with cystic fibrosis M. Proesmans, F. Vermeulen,

Early and long-term results of carotid endarterectomy in diabetic patients Walter Dorigo, MD, Raffaele Pulli, MD, Giovanni Pratesi, MD, Aaron Fargion,

Periodic pharyngolaryngoscopy detects early head and neck cancer and improves survival in esophageal cancer Akihito Watanabe, MD, Masao Hosokawa, MD,

A Model to Predict the Use of Surgical Resection for Advanced-Stage Non-Small Cell Lung Cancer Patients Elizabeth A. David, MD, Stina W. Andersen, PhD,

Castigliano M. Bhamidipati, DO, MS, George J

The Model for End-Stage Liver Disease (MELD) Predicts Early and Late Outcomes of Cardiovascular Operations in Patients With Liver Cirrhosis Naoto Morimoto,

Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer Robert E. Merritt, MD, Chuong D. Hoang, MD,

Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.

Does female gender or hormone replacement therapy affect early or late outcome after carotid endarterectomy? John S. Lane, MDa, Shant Shekherdimian,

Does bariatric surgery reduce the risk of major cardiovascular events

Asad A. Shah, MD, Mathias Worni, MD, MHS, Christopher R

Kaplan-Meier curves comparing: (A) overall survival for patients treated on trial compared to those outside of a trial; (B) progression-free survival for.

Impact of Positive Nodal Metastases in Patients with Thymic Carcinoma and Thymic Neuroendocrine Tumors Benny Weksler, MD, Anthony Holden, MD, Jennifer.

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries British Journal of Anaesthesia

A.H. Gifford Journal of Cystic Fibrosis

Gender differences in treatment outcomes of tuberculosis patients in Taiwan: a prospective observational study J.-Y. Feng, S.-F. Huang, W.-Y. Ting, Y.-C.

Elliot Wakeam, MD, MPH, James P. Byrne, MD, Gail E

• Kaplan-Meier analyses of (A) overall survival (OS) of the whole cohort (n=173), (B) OS from time of diagnosis of high-risk melanoma among those who remained.

Katelynn M. Ferranti, MD, Turner M. Osler, MD, Reshma P

Volume 9, Issue 4, Pages (April 2008)

Michael Lanuti, MD, Pierre E

Matthew J. Bott, MD, Hanghang Wang, BA, William Travis, MD, Gregory J

Appropriateness of Surgical Approach in Black Patients with Lung Cancer—15 Years Later, Little Has Changed Emanuela Taioli, MD, PhD, Raja Flores, MD

Ali Azizzadeh, MD, Kristofer M

Is the B12/CRP Index More Accurate Than You at Predicting Life Expectancy in Advanced Cancer Patients? Filipa Tavares, MD Journal of Pain and Symptom.

Extent of Lymphadenectomy Is Associated With Improved Overall Survival After Esophagectomy With or Without Induction Therapy Pamela Samson, MD, MPHS,

Volume 371, Issue 9618, Pages (March 2008)

Bypass for chronic ischemia of the upper extremity: Results in 20 patients Kakra Hughes, MD, Allen Hamdan, MD, Marc Schermerhorn, MD, Anthony Giordano,

Determinants of mortality and treatment outcome following surgical interventions for acute mesenteric ischemia Panagiotis Kougias, MD, Donald Lau, BS,

Chung-Dann Kan, MD, Hsin-Ling Lee, MD, Yu-Jen Yang, MD, PhD

Heterogeneity of Lung Volume Reduction Surgery Outcomes in Patients Selected by Use of Evidence-Based Criteria Matthew R. Lammi, MD, Nathaniel Marchetti,

Early versus delayed carotid endarterectomy in symptomatic patients

It’s All in the “Swerve of the Curve”

Interferon alfa-2a for melanoma metastases

E.Stanley Crawford, M.D., Ralph W. DeNatale, M.D.

Identification of patients at risk of metastasis using a prognostic 31-gene expression profile in subpopulations of melanoma patients with favorable outcomes.

The Impact of Volume Reduction on Early and Long-Term Outcomes in Surgical Ventricular Restoration for Severe Heart Failure Nathan Wm. Skelley, BS, Jeremiah.

Predictors of decreased short- and long-term survival following open abdominal aortic aneurysm repair Derek P. Nathan, MD, Clayton J. Brinster, MD, Benjamin.

Immediate and Long-Term Survival After Surgery for Lung Cancer in Heart Transplant Recipients Patrick Bagan, MD, Jalal Assouad, MD, Pascal Berna, MD,

Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.

Pleurodesis for primary spontaneous pneumothorax – Authors' reply

• Kaplan-Meier analyses of (A) time-to-recurrence (TTR) for the subgroup of patients with high-risk melanoma who had relapsed (n=82), (B) recurrence-free.

Axillary-to-carotid artery bypass grafting for symptomatic severe common carotid artery occlusive disease Joseph P. Archie, PhD, MD Journal of Vascular.

Results of a single center vascular screening and education program

Time Trends of Surgical Outcome in Patients with Non-small Cell Lung Cancer Takeshi Hanagiri, MD, PhD, Tetsuro Baba, MD, PhD, Tetsuya So, MD, PhD, Manabu.

Early Surgical Results After Pneumonectomy for Non-Small Cell Lung Cancer are not Affected by Preoperative Radiotherapy and Chemotherapy Tomas Gudbjartsson,

Long-Term Results of Sleeve Lobectomy in the Management of Non–Small Cell Lung Carcinoma and Low-Grade Neoplasms Robert E. Merritt, MD, Douglas J. Mathisen,

Kristin A. Higgins, MD, Junzo P. Chino, MD, Neal Ready, MD, Mark W

Presentation transcript:

Survival outcomes and interval between lymphoscintigraphy and SLNB in cutaneous melanoma- findings of a large prospective cohort study Fionnuala M. O'Leary, Clare J. Beadsmoore, Davina Pawaroo, John Skrypniuk, Martin J. Heaton, Marc D. Moncrieff European Journal of Surgical Oncology Volume 44, Issue 11, Pages 1768-1772 (November 2018) DOI: 10.1016/j.ejso.2018.06.011 Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology Terms and Conditions

Fig. 1 Comparison of distribution of timing of lymphoscintigraphy by year. Patients were divided into two cohorts (2008–2011 and 2012–2015) and the proportion of patients undergoing lymphoscintigraphy early (<12 h) was compared with late (>12 h). The results show showed a decrease in early lymphoscintigraphy rate from 40.8% to 31.6% in the second cohort (Chi squared test p = 0.002). European Journal of Surgical Oncology 2018 44, 1768-1772DOI: (10.1016/j.ejso.2018.06.011) Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology Terms and Conditions

Fig. 2 Comparison of OS, DSS and nodal relapse rates in early versus late treatment groups. 2A Kaplan Meier survival curve, which shows that there is a reduction in OS of 10.6% (p = 0.01, HR 1.64 [1.13–2.38]) in patients undergoing SLNB > 12 h post Tc-99 m nanocolloid injections. 2B Kaplan Meier survival curve, which shows a significant reduction (p = 0.04) in DSS in patients undergoing SLNB > 12 h post Tc-99 m nanocolloid injections. 2C Kaplan Meier survival curve which does not show any significant difference (p = 0.67) in nodal relapse rates between early versus late treatment groups. European Journal of Surgical Oncology 2018 44, 1768-1772DOI: (10.1016/j.ejso.2018.06.011) Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology Terms and Conditions

Fig. 3 Comparison of OS in treatment groups according to time course. OS is compared between groups patients undergoing Tc99m-nanocolloid injections 6, 9, 12 and 18 h prior to sentinel lymph node biopsy using Kaplan Meier curves. The results show a significant difference (p < 0.003) between patients undergoing early versus late lymphoscintigraphy, with the greatest difference observed at 12 h. European Journal of Surgical Oncology 2018 44, 1768-1772DOI: (10.1016/j.ejso.2018.06.011) Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology Terms and Conditions