Morphine-Methadone Opioid Rotation in Cancer Patients: Analysis of Dose Ratio Predicting Factors  Miguel Angel Benítez-Rosario, MD, PhD, Antonio Salinas-Martín,

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Morphine-Methadone Opioid Rotation in Cancer Patients: Analysis of Dose Ratio Predicting Factors  Miguel Angel Benítez-Rosario, MD, PhD, Antonio Salinas-Martín, MD, Armando Aguirre-Jaime, MSc, Lina Pérez-Méndez, MD, PhD, Manuel Feria, DSc, PhD  Journal of Pain and Symptom Management  Volume 37, Issue 6, Pages 1061-1068 (June 2009) DOI: 10.1016/j.jpainsymman.2008.05.016 Copyright © 2009 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Correlation between MMEDR on Day 10 and the morphine dose administered before the switch. Each dot represents one patient (n=54 patients). Spearman rho is correlation coefficient. Solid and dashed lines represent best-fit straight line and 95% confidence intervals, respectively. Journal of Pain and Symptom Management 2009 37, 1061-1068DOI: (10.1016/j.jpainsymman.2008.05.016) Copyright © 2009 U.S. Cancer Pain Relief Committee Terms and Conditions