Volume 127, Issue 2, Pages (August 2004)

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Volume 127, Issue 2, Pages 412-421 (August 2004) High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease Arlette Darfeuille-Michaud, Jérôme Boudeau, Philippe Bulois, Christel Neut, Anne-Lise Glasser, Nicolas Barnich, Marie-Agnès Bringer, Alexander Swidsinski, Laurent Beaugerie, Jean-Frédéric Colombel Gastroenterology Volume 127, Issue 2, Pages 412-421 (August 2004) DOI: 10.1053/j.gastro.2004.04.061

Figure 1 Transmission electron micrographs of Intestine-407 cells infected with strain LF82. (A) Cross-section of the intestinal epithelial cell monolayer showing membrane ruffling on contact with the bacteria after a 3-hour infection period. Bacteria are engulfed by elongated microvilli from the infected intestinal epithelial cell. (B) Micrograph showing numerous intracellular bacteria after a 5-hour infection period. (A) Magnification 13,300×, (B) magnification 4500×. Gastroenterology 2004 127, 412-421DOI: (10.1053/j.gastro.2004.04.061)