Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures

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Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures Anthony P Furnary, MD, Kathryn J Zerr, MBA, Gary L Grunkemeier, PhD, Albert Starr, MD The Annals of Thoracic Surgery Volume 67, Issue 2, Pages 352-360 (February 1999) DOI: 10.1016/S0003-4975(99)00014-4

Fig 1 Distribution curves of mean glucose levels on POD 1 in patients in the CII study group (A) and control (SQI) group (B). Vertical line represents the desired goal of 200 mg/dL. Tighter glucose control with CII is reflected by the fact that 85% of the CII study group successfully achieved levels below 200 mg/dL. In the SQI control group, in contrast, there is only a 47% compliance with target levels. The Annals of Thoracic Surgery 1999 67, 352-360DOI: (10.1016/S0003-4975(99)00014-4)

Fig 2 Daily comparison of mean blood glucose levels between patients with DSWI and those without DSWI (No DSWI). (∗p = 0.02; #p = 0.01.) The Annals of Thoracic Surgery 1999 67, 352-360DOI: (10.1016/S0003-4975(99)00014-4)

Fig 3 Annual rates of DSWI in diabetic and nondiabetic patients after cardiac surgical procedures at Providence St Vincent Medical Center from 1987 through 1997. Note the significant downward trend (slope, −0.52%/year, p = 0.03) since the implementation of the CII protocol. Diabetic DSWI rates since 1995 appear to have normalized to that of the nondiabetic population. (DM = diabetes mellitus; Pts. = patients.) The Annals of Thoracic Surgery 1999 67, 352-360DOI: (10.1016/S0003-4975(99)00014-4)