EWS RNA-binding protein What does this protein make up or do? Chapter 22: Chromosome 22 DNA Sequence Chromosome 32,517 bp Name of Protein 22 Name of Gene EWS RNA-binding protein EWSR1 transcription Amino acid sequence mRNA 655 aa ConditionDisease/ EWSR1 is known to cause Ewing sarcoma as well as neuroectodermal and other tumors translation What does this protein make up or do? This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. A Cell Nucleus

Description of ewing sarcoma Symptoms and characteristics Pain and/or swelling, usually in the arms, legs, chest, back, or pelvis (area between the hips). A lump that may feel soft and warm in the arms, legs, chest, or pelvis. typically starts in the bones, but can also start in other tissues and muscles. It is the third most common form of primary bone cancer. Ewing sarcoma normal http://www.radiologyassistant.nl/en/p494e15cbf0d8d/bone-tumor-systematic-approach-and-differential-diagnosis.html

Description of ewing sarcoma (cont.) Who is affected? Anyone, but the following have a higher risk: It occurs most frequently in children and teenagers, and is rarely seen in adults over the age of 30. Outlook or quality of life the 5-year survival rate has increased over the same time from 59% to 78% for kids younger than 15 and from 20% to 60% for adolescents aged 15 to 19 . Childhood and young adult cancer survivors require close follow-up because cancer therapy side effects could stay or develop years or months after treatment. Researcher: TR

References http://www.cancer.gov/cancertopics/pdq/treatment/ewings/HealthProfessional/page1 http://www.ncbi.nlm.nih.gov/gene/2130 https://www.google.com/search?q=googlg&sourceid=ie7&rls=com.microsoft:en-US:IE-Address&ie=&oe=&gws_rd=ssl#rls=com.microsoft:en-US:IE-Address&q=symptoms+of+ewing+sarcoma