CaV1.2 Calcium Channels: Just Cut Out to Be Regulated?

Slides:

Advertisements

Similar presentations

The Pore Helix Dipole Has a Minor Role in Inward Rectifier Channel Function Franck C. Chatelain, Noga Alagem, Qiang Xu, Raika Pancaroglu, Eitan Reuveny,

Advertisements

Expectation Modulates Neural Responses to Pleasant and Aversive Stimuli in Primate Amygdala Marina A. Belova, Joseph J. Paton, Sara E. Morrison, C. Daniel.

The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages (September 2009) DOI:

Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies B.J. Casey, Charles E. Glatt, Francis S. Lee Neuron Volume.

NMDA Receptors in Dopaminergic Neurons Are Crucial for Habit Learning Lei Phillip Wang, Fei Li, Dong Wang, Kun Xie, Deheng Wang, Xiaoming Shen, Joe Z.

Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics Timothy P. Lillicrap, Stephen H. Scott.

The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.

Intensity-Dependent Adaptation of Cortical and Thalamic Neurons Is Controlled by Brainstem Circuits of the Sensory Pathway Elad Ganmor, Yonatan Katz, Ilan.

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release Peng Zhou, Taulant Bacaj, Xiaofei Yang,

Decision Making as a Window on Cognition Michael N. Shadlen, Roozbeh Kiani Neuron Volume 80, Issue 3, Pages (October 2013) DOI: /j.neuron

Canonical Microcircuits for Predictive Coding Andre M. Bastos, W. Martin Usrey, Rick A. Adams, George R. Mangun, Pascal Fries, Karl J. Friston Neuron Volume.

Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages (June 2006) DOI: /j.neuron

AMPA Receptor Signaling through BRAG2 and Arf6 Critical for Long-Term Synaptic Depression Ralf Scholz, Sven Berberich, Louisa Rathgeber, Alexander Kolleker,

GDE2 Regulates Subtype-Specific Motor Neuron Generation through Inhibition of Notch Signaling Priyanka Sabharwal, Changhee Lee, Sungjin Park, Meenakshi.

ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Auditory Hair Cell-Afferent Fiber Synapses Are Specialized to Operate at Their Best Frequencies M.E. Schnee, D.M. Lawton, D.N. Furness, T.A. Benke, A.J.

Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)

Single Units in the Medial Prefrontal Cortex with Anxiety-Related Firing Patterns Are Preferentially Influenced by Ventral Hippocampal Activity Avishek.

Multiscale Optical Ca2+ Imaging of Tonal Organization in Mouse Auditory Cortex John B. Issa, Benjamin D. Haeffele, Amit Agarwal, Dwight E. Bergles, Eric.

Normal Movement Selectivity in Autism Ilan Dinstein, Cibu Thomas, Kate Humphreys, Nancy Minshew, Marlene Behrmann, David J. Heeger Neuron Volume 66, Issue.

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka.

Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.

Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons Mitsuko Watabe-Uchida, Lisa Zhu, Sachie K. Ogawa, Archana Vamanrao, Naoshige Uchida Neuron.

The Relationship of Anatomical and Functional Connectivity to Resting-State Connectivity in Primate Somatosensory Cortex Zheng Wang, Li Min Chen, László.

Pyramidal Neurons Grow Up and Change Their Mind Gord Fishell, Carina Hanashima Neuron Volume 57, Issue 3, Pages (February 2008) DOI: /j.neuron

Hippocampal Activity Patterns Carry Information about Objects in Temporal Context Liang-Tien Hsieh, Matthias J. Gruber, Lucas J. Jenkins, Charan Ranganath.

Disrupted Neural Synchronization in Toddlers with Autism Ilan Dinstein, Karen Pierce, Lisa Eyler, Stephanie Solso, Rafael Malach, Marlene Behrmann, Eric.

Dissociable Medial Prefrontal Contributions to Judgments of Similar and Dissimilar Others Jason P. Mitchell, C. Neil Macrae, Mahzarin R. Banaji Neuron.

Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron

Adaptation to Natural Binocular Disparities in Primate V1 Explained by a Generalized Energy Model Ralf M. Haefner, Bruce G. Cumming Neuron Volume 57, Issue.

Reading the Book of Memory: Sparse Sampling versus Dense Mapping of Connectomes H. Sebastian Seung Neuron Volume 62, Issue 1, Pages (April 2009)

Rare Inherited Variation in Autism: Beginning to See the Forest and a Few Trees Jason L. Stein, Neelroop N. Parikshak, Daniel H. Geschwind Neuron Volume.

Neuronal Synchronization along the Dorsal Visual Pathway Reflects the Focus of Spatial Attention Markus Siegel, Tobias H. Donner, Robert Oostenveld, Pascal.

Building Better Models of Visual Cortical Receptive Fields

CA3 Sees the Big Picture while Dentate Gyrus Splits Hairs

Volume 1, Issue 1, Pages (June 2007)

Volume 92, Issue 2, Pages (October 2016)

Alexander Stein, Reinhard Jahn Neuron

Calcium Signaling and the Control of Dendritic Development

Calcium Signals Control Wnt-Dependent Dendrite Growth

The Rising Tide of tDCS in the Media and Academic Literature

Hippocalcin: A New Solution to an Old Puzzle

Tiki Casts a Spell on Wnt

A Code for Cross-Modal Working Memory

Christopher J. Tabone, Mani Ramaswami Neuron

Chapter 65 - The Hormonal Regulation of Calcium Metabolism

There's More Than One Way to Scale a Synapse

Applying the Brakes: When to Stop Eating

Volume 68, Issue 2, Pages (October 2010)

Emotional Pain without Sensory Pain—Dream On?

Volume 55, Issue 3, Pages (August 2007)

Recurrent Feedback Loops in Associative Learning

Bringing Kids into the Scientific Review Process

K+ Channel Regulation of Multicompartmental Signal Integration

Aligning a Synapse Neuron

Do Flies Count Sheep or NMDA Receptors to Go to Sleep?

Watching the Fly Brain Learn

Volume 91, Issue 6, Pages (September 2016)

Beta and Gamma Rhythms Go with the Flow

Mark J. Buckley, Natasha Sigala Neuron

Brain Canada: One Brain One Community

Volume 49, Issue 5, Pages (March 2006)

Diego Varela, Gerald W. Zamponi Neuron

Patterns of fMRI Activity Dissociate Overlapping Functional Brain Areas that Respond to Biological Motion Marius V. Peelen, Alison J. Wiggett, Paul E.

Anatomical Plasticity of Adult Brain Is Titrated by Nogo Receptor 1

The Cost of Brain Diseases: A Burden or a Challenge?

Brain Canada: One Brain One Community

David Hubel and Torsten Wiesel

PKC Defends Crown Against Munc13

Opening a “Wide” Window onto Taste Signal Transmission

Presentation transcript:

CaV1.2 Calcium Channels: Just Cut Out to Be Regulated? Rachel D. Groth, Natasha N. Tirko, Richard W. Tsien Neuron Volume 82, Issue 5, Pages 939-940 (June 2014) DOI: 10.1016/j.neuron.2014.05.030 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Midbody Proteolytic Cleavage of the Basic CaV1.2 Pore-Forming Unit This Ca2+-dependent cleavage, here illustrated for the II-III linker (left), gives rise to fragments that can remain together in a functional state (top right). The fragments can also dissociate and form a mosaic pattern in the surface membrane (bottom right), raising questions about their possible functional significance. Neuron 2014 82, 939-940DOI: (10.1016/j.neuron.2014.05.030) Copyright © 2014 Elsevier Inc. Terms and Conditions