Tick-borne encephalitis (TBE) virus prevalence and virus genome characterization in field-collected ticks (Ixodes ricinus) from risk, non-risk and former.

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Presentation transcript:

Tick-borne encephalitis (TBE) virus prevalence and virus genome characterization in field-collected ticks (Ixodes ricinus) from risk, non-risk and former risk areas of TBE, and in ticks removed from humans in Germany C. Klaus, B. Hoffmann, U. Hering, B. Mielke, K. Sachse, M. Beer, J. Süss Clinical Microbiology and Infection Volume 16, Issue 3, Pages 238-244 (March 2010) DOI: 10.1111/j.1469-0691.2009.02764.x Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Sites of tick collections in 2005 and 2006, showing: Sassnitz and Königsstuhl, Isle of Rügen, Mecklenburg-Western Pomerania; Neustrelitz, around Lake Woblitzsee, Mecklenburg-Western Pomerania; Colbitz-Letzlinger Heide and surroundings, Saxony-Anhalt; Hainich National Park, and the Thuringia districts (Bavaria) in which volunteers lived. For a map, see http://www.zecken.de/index.php?id = 500. TBE, tick-borne encephalitis. Clinical Microbiology and Infection 2010 16, 238-244DOI: (10.1111/j.1469-0691.2009.02764.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Sites where engorged ticks were collected from volunteers: Rosenheim, Miesbach, Mühldorf, Berchtesgadener Land, Ebersberg, Traunstein, Munich and Altötting (Bavaria). Clinical Microbiology and Infection 2010 16, 238-244DOI: (10.1111/j.1469-0691.2009.02764.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 Neighbour-joining tree showing the relationships between nucleotide sequences of the C-genes and E-genes of selected strains of tick-borne encephalitis virus (TBEV). The tree was constructed using distance matrices generated with the p-distance determination algorithm in MEGA 4 (2000 bootstrap replicates) [14]. Numbers indicate bootstrap confidence values after 2000 replications. Scale bar indicates nucleotide substitutious per site. Clinical Microbiology and Infection 2010 16, 238-244DOI: (10.1111/j.1469-0691.2009.02764.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions