Effects of synbiotics on intestinal mucosal barrier in rat model

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Effects of synbiotics on intestinal mucosal barrier in rat model Zhigang Xue, Jianchun Yu, Mingli Zhao, Weiming Kang, Zhiqiang Ma Clinical Nutrition Experimental Volume 13, Pages 12-21 (June 2017) DOI: 10.1016/j.yclnex.2017.02.001 Copyright © 2017 Terms and Conditions

Fig. 1 The flow chart of this study design. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 2 Body weights of rats in control group (n = 8), probiotics group (n = 8), prebiotics group (n = 8) and synbiotics group (n = 8) before and after cecectomy and gastrostomy. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 3 Percentage of weight loss in four groups, P = 0.577. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 4 Lactobacilli concentration of colonic contents in four groups postoperatively. * means significant difference when compared to control group, P < 0.05. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 5 Bifidobacteria concentration of colonic contents in four groups postoperatively. * means significant difference when compared to control group, P < 0.05. **means significant difference when compared to probiotics group, P < 0.05. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 6 10-base logarithm of gram-negative bacteria (log1) to 10-base logarithm of bifidobacteria concentration (log2) ratio value. * means significant difference when compared to control group, P < 0.05. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 7 Lactulose to mannitol ratio in four groups. * means significant difference when compared to control group, P < 0.05. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions

Fig. 8 Colon mucosa thickness in four groups on POD6. * means significant difference when compared to control group, P < 0.01. Clinical Nutrition Experimental 2017 13, 12-21DOI: (10.1016/j.yclnex.2017.02.001) Copyright © 2017 Terms and Conditions