Figure 3 Geometric mean titer ratio and seroprotection at week 4

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Figure 3 Geometric mean titer ratio and seroprotection at week 4 Geometric mean titer ratio and seroprotection at week 4 (A) Geometric mean titer ratio and (B) seroprotection at week 4. All patients entering the study had protective levels against diphtheria. The protective level was based on American Academy of Allergy, Asthma & Immunology guidance for diagnostic vaccines; it is an active area of research.13 Protective levels were 0.15 IU/mL for tetanus, 0.01 IU/mL for diphtheria, 1.3 μg/mL for pneumococcal serotypes 3 and 8, and 2.0 μg/mL for meningococcal serogroup C. The proportion of patients with protective antibody titers/number of patients in the group is shown. BID = twice daily; DMF = delayed-release dimethyl fumarate; IFN = interferon. Christian von Hehn et al. Neurol Neuroimmunol Neuroinflamm 2018;5:e409 Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.