a+ --> a- mutation (forward mutation)

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Presentation transcript:

a+ --> a- mutation (forward mutation) a- --> a+ reverse mutation (reversion)

Presence of pink pigment + / - Four-o’clock plants Incomplete dominance the term used to describe the general case in which the phenotype of a heterozygote is intermediate between those of the two homozygotes, on some quantitative scale of measurement

Point mutations at the molecular level

Now, insertions and deletions of base pairs:

Intragenic suppressor Equivalent reversion UCC (Ser) forward UGC (Cys) reverse AGC (Ser) Wild type Mutant Wild type CGC (Arg, basic) forward CCC (Proline) reverse CAC (His, basic) Wild type Mutant Pseudo-wild type

Intragenic suppressor

Intergenic suppressor

Intergenic suppressor Nonsense suppressor

Regulatory Coding

A situation in which the third nucleotide WOBBLE A situation in which the third nucleotide of an anticodon (at the 5’ end) can form two alignments. This third nucleotide can form hydrogen bonds not only with its normal complementary nucleotide in the third position but also with different nucleotide in the position.

I stands for inosine, one of the rare bases found in tRNA, often in anticodon

The genetic code is said to be degenerate because in many cases MESSAGE The genetic code is said to be degenerate because in many cases more then one codon is assigned to a single amino acid, and, in addition, several codons can pair with more then one anticodon (wobble)