Influenza Vaccines: Challenges and Solutions

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Presentation transcript:

Influenza Vaccines: Challenges and Solutions Katherine Houser, Kanta Subbarao  Cell Host & Microbe  Volume 17, Issue 3, Pages 295-300 (March 2015) DOI: 10.1016/j.chom.2015.02.012 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Stages of the Viral Life Cycle and Vaccine Targets Many stages of viral infection can be targeted by vaccines; the targets of the vaccines described in this review are indicated. Vaccines that elicit an immune response that blocks a stage in the viral life cycle are shown in red, while vaccines that activate a specific host immune response are shown in green. Abbreviations: IIV: inactivated influenza vaccine; LAIV: live attenuated influenza vaccine; COBRA: computationally optimized broadly reactive antigen; HA: hemagglutinin; ADCC: antibody dependent cell cytotoxicity Cell Host & Microbe 2015 17, 295-300DOI: (10.1016/j.chom.2015.02.012) Copyright © 2015 Elsevier Inc. Terms and Conditions

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