Benefit of ELISpot in early diagnosis of tuberculous meningoencephalitis: Case report and literature review Josefine Blume, Josef Köstler, Robert Weissert

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Benefit of ELISpot in early diagnosis of tuberculous meningoencephalitis: Case report and literature review Josefine Blume, Josef Köstler, Robert Weissert eNeurologicalSci Volume 1, Issue 3, Pages 51-53 (September 2015) DOI: 10.1016/j.ensci.2015.10.004 Copyright © 2015 The Authors Terms and Conditions

Fig. 1 Cerebral MRI at onset of neurological symptoms (A) and after two weeks of therapy with anti-mycobacterial agents (B) in axial fluid-attenuated inversion recovery (FLAIR) images. (C) ELISpot for detection of immune reactivity against mycobacterial antigens with lymphocytes from blood and CSF of a patient with tuberculous meningoencephalitis. Number of spots indicating T lymphocytes that have secreted IFN-γ in response to the mycobacterial antigens, ESAT-6 or/and CFP-10, as well as to the mitogen phytohemagglutinin (PHA) from blood and CSF are shown. TNTC indicates too numerous to count. eNeurologicalSci 2015 1, 51-53DOI: (10.1016/j.ensci.2015.10.004) Copyright © 2015 The Authors Terms and Conditions