Immune System Pt 2 -There are three general cells involved with an immune response: -phagocytes -B lymphocytes (B cells) -T lymphocytes (T cells) Phagocytes/Macrophages -Phagocytes move through the circulatory system consuming waste and foreign material, such as aged or damaged blood cells and some infectious bacteria and viruses -helps in recognizing antigens
Immune System Pt 2 B Cells -matures in the bone marrow -able to recognize antigens -antibody-producing cells that are responsible for humoral immunity (immunity by macromolecules) -Each B-lymphocyte can give rise to only a single type of antibody, which itself may recognize only a single foreign antigen
Immune System Pt 2 T Cells -matures in the thymus gland -2 kinds: “cytotoxic” (cell killing) and “helper” T-lymphocytes. -The cytotoxic T-cells are useful for surveillance and elimination of intra-cellular pathogens (Antibodies cannot reach the intracellular pathogen because of the cell membrane, but the infected cell can be identified and killed) -Helper T-cells assist in organizing both the humoral and cellular immune responses.
Immune System Analogy Develop an analogy for your immune system. Think of war as a scenario. Your body would be the stronghold to be defended. As you create your analogy, be sure to include a picture and link parts of your analogy to the things below: Skin – first line of defense Pathogen – the “bad guys” Antigen – how “bad guys” are identified Antibodies – how “bad guys” are flagged for destruction B cells, Macrophages – the “good guys” that help identify invaders Helper T cells – organizers of the immune response Killer T cells – the “good guys” that help destroy the invaders