4/23/2017 The Africa Centre of Excellence for Infectious Diseases of Humans and Animals (ACEIDHA) Professor Aaron Mweene, Centre Leader ACE II Technical and Advisory Meeting May 9-10, 2018 LUSAKA, ZAMBIA

Establishment of ACEIDHA 4/23/2017 Establishment of ACEIDHA The ACEIDHA has been established at the University of Zambia through the World Bank Project for Eastern and Southern Higher Education Centers of Excellence initiative Is a loan to the Government and a grant to UNZA It is hosted at the School of Veterinary Medicine

African highly dangerous pathogens 4/23/2017 Increased emergence and re-emergence of disease such as Ebola virus infections, pneumonic plague, anthrax, trypanosomiasis and neglected tropical diseases (NTDs) in Africa including in new geographic areas High health and socio-economic impacts, and pose serious biosafety and biosecurity challenges Ironically, Africa has least capacity for their risk management and control

ACEIDHA – Steps to effectiveness Project approval: 26 May 2016 End date: 31 Dec 2022 Total amount: US$ 6.0m Zambia ACE II Launch: 26April, 2018 ACEIDHA effectiveness - 26 October, 2017 Disbursement US$1.1m for DLI#1 achievement - February, 2018 Designated ACEIDHA US$ Account has been opened at BOZ ACEIDHA bank accounts at Standard Chartered Bank ($ & ZMW) Signatories - Panel A - UNZA Bursar’s Department Panel B - ACEIDHA members and Dean, Veterinary Medicine

ACEIDHA Educational and Research goals PhD (20) and MSc (80) levels training to develop critical mass of skilled human resources to both the private and public sectors Strengthen network/linkages with local, regional and international institutions Produce qualified manpower as future teaching and research faculty Develop advocacy programs for community and policy formulation Develop infectious disease counter measures Elucidate the ecology of the pathogens

ACEIDHA – Project Management Team Centre Leader, Deputy Centre Leader, X5 Theme Coordinators Financial Management: Office of UNZA Bursar - X2 Accountants Procurement: UNZA Purchase and Supplies Unit - X2 Procurement officers Audit: UNZA Audit Department Communication: UNZA Public relations & International Liaison Officers have been designated as ACEIDHA Communication Officers

ACEIDHA Implementation arrangement National Steering Committee UNZA Vice Chancellor Center Leader-Prof. Aaron Mweene Deputy Center Leader-Prof. Bernard Hang’ombe Thematic Leaders and other members of Project Management Team ISAB Industry partners National Academic partners International teaching institutions International diagnostic laboratories Faculty Students Admin staff Learning/research infrastructure Regional diagnostic laboratories Regional teaching institutions

ACEIDHA Training and Research Themes Emerging and re-emerging infectious diseases of viral origin and Zoonosis Bacterial zoonoses and antimicrobial resistance Vector borne emerging diseases Neglected Tropical Diseases (NTDs)

ACEIDHA Program of Activities Partners Curriculum development PhD, MSc training Pathogen surveillance Pathogen isolation Pathogen detection Serologic Genomic-based Identification of reservoirs Risk assessment PhD, MSc training Molecular analysis Biological characterisation Improvement of existing diagnostic procedures Next generation sequencing Development of novel diagnostic tests Discovery of novel pathogens Human resource exchange/Information sharing

ACEIDHA – on going activities Development of new MSc courses and review of existing ones One Health Food Safety One Health Analytical Epidemiology One Health Infectious Diseases Eco Health Systems Infectious Disease and Zoonosis One Health Laboratory diagnostics Accreditation of MSc programmes – Higher Education Authority Recruitment of students (local and regional) -overwhelming (80 PhD and over 200 MSc applications from 14 countries) Establishment of joint International Scientific Advisory Board (ISAB) with SACIDS ACE in Tanzania

ACEIDHA – on going activities Recruitment of ACEIDHA staff -Centre Manager, -Senior Administrative -Officer, Driver Rehabilitation of centre infrastructure Procurement of motor vehicles (x2) Consolidation of partnerships - local, - regional, - international Grant applications (jointly with partners)

Partnerships – Universities Intra School of Medicine School of Public Health School of Nursing School of Biomedical Sciences Local Copperbelt University, School of Medicine Regional Sokoine University of Agriculture Muhimbili University of Health and Allied Sciences International Hokkaido University University College Dublin

Partnerships – Research Institutions Local Tropical Diseases Research Centre (TDRC) Central Veterinary Research Institute (CVRI) Zambia National Public Health Institute (ZNPHI)/ Regional Collaboration Centre of Africa CDC – (in progress) Regional Southern African Centre for Infectious Disease of Humans and Animals (SACIDS) International Research Centre for Zoonosis Control (CZC) Global Virus Network (40 CoEs and 07 Affiliates in 25 countries)

ACEIDHA has been approved as a New Affiliate Member of Global Virus Network  4/23/2017 ACEIDHA’s membership is sponsored by two GVN Centers of Excellence, Hokkaido University and University College Dublin A novel collaborative model whereby a GVN Affiliate member in Africa has been ‘twinned’ with GVN Centers in Japan and Ireland, to maximize Synergies and Mobility of Scientists ACEIDHA’s status at the GVN, enables it to better train virologists at MSc, PhD and post-doctoral levels.  ACEIDHA will help GVN members facilitate interactions with a number of partners in Africa, which is critical to GVN’s mission in preparing the world for future outbreaks of viral diseases.  www.gvn.org (12 Jan 2018)

ACEIDHA Challenges International/regional accreditation of training programmes Fostering partnerships/collaborations with industry Governance/implementation arrangement yet to be fully understood/appreciated in the university Procurement process too long

ACEIDHA remedial measures Continuous and timely engagement with UNZA ‘s managerial, administrative and academic staff on operations of ACEIDHA National steering committee to continuously support ACEIDHA Country World Bank team/IUCEA (ACE II RFU) should provide continuous technical and implementation support including financial management, procurement, disbursement, and safeguards

ACEIDHA Thank you for your attention