Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese Ping-Ping Cao, MD, Hua-Bin Li, MD, PhD, Bao-Feng.

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Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese Ping-Ping Cao, MD, Hua-Bin Li, MD, PhD, Bao-Feng Wang, MD, Shui-Bin Wang, MD, Xue-Jun You, MD, PhD, Yong-Hua Cui, MD, De- Yun Wang, MD, PhD, Martin Desrosiers, MD, Zheng Liu, MD, PhD Journal of Allergy and Clinical Immunology Volume 124, Issue 3, Pages 478-484.e2 (September 2009) DOI: 10.1016/j.jaci.2009.05.017 Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 mRNA expression levels or expression rate of transcription factors and cytokines of T cell subsets, and a marker of NKT cell (Valpha24) in various types of CRS. TH1 cells transcription factor T-bet (A) and cytokine IFN-gamma (B); TH2 cells transcription factor GATA-3 (C) and cytokine IL-5 (D); TH17 cells transcription factor RORC (E) and cytokines IL-17A (F), IL-22 (G) and IL-23 ( H); Treg cells transcription factor FOXP3 (I) and cytokines TGF-beta1 (J) and IL-10 ( K) and NKT cell marker Valpha24 (L) were measured by quantitative RT-PCR. EOS CRSwNP, Eosinophilic CRSwNP; Non-EOS CRSwNP, noneosinophilic CRSwNP. ∗P < .05; ∗∗P < .01. Journal of Allergy and Clinical Immunology 2009 124, 478-484.e2DOI: (10.1016/j.jaci.2009.05.017) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions