Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis  Julia Baumgartl, Stephanie Baudler, Maximilian Scherner, Vladimir R. Babaev, Liza Makowski, Jill Suttles, Marcia McDuffie, Kazuyuki Tobe, Takashi Kadowaki, Sergio Fazio, C. Ronald Kahn, Gökhan S. Hotamisligil, Wilhelm Krone, MacRae F. Linton, Jens C. Brüning  Cell Metabolism  Volume 3, Issue 6, (June 2006) DOI: 10.1016/j.cmet.2006.05.008 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 4 Impaired inflammatory response in insulin-resistant macrophages A) Northern blot analysis of MCP1, TNF-α, IL-1β, and IL-6 expression in IRflox/flox immortalized macrophage cell lines treated without (WT) or with HNTC-Cre (KO), which have been cultured either in the absence or presence of 10 ng/ml LPS for 24 hr. Cell Metabolism 2006 3, DOI: (10.1016/j.cmet.2006.05.008) Copyright © 2006 Elsevier Inc. Terms and Conditions