Male contraception Fertility and Sterility

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Presentation transcript:

Male contraception Fertility and Sterility John K. Amory, M.D., M.P.H. Fertility and Sterility Volume 106, Issue 6, Pages 1303-1309 (November 2016) DOI: 10.1016/j.fertnstert.2016.08.036 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Normal function of the hypothalamic-pituitary-testicular axis, with FSH and LH stimulating the testes to produce sperm and testosterone, and testosterone providing feedback regulation of FSH and LH production in the pituitary. (B) Suppression of FSH and LH production by exogenously administered androgens and progestins, which lowers FSH and LH concentrations, depriving the testes of the signals required for sperm production and leading to contraception. Fertility and Sterility 2016 106, 1303-1309DOI: (10.1016/j.fertnstert.2016.08.036) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions