PAH Therapy Revisited

Prostacyclin Pathway in PAH

Case Scenario Presentation

Case Scenario Workup

Case Scenario Treatment

Case Scenario Right Heart Catheterization for PAH Diagnosis

Intravenous Epoprostenol vs Conventional Therapy in PAH

Therapies Targeting the Prostacyclin Pathway

Case Scenario

Transition From Inhaled to Parenteral Treprostinil Rescues PAH Patients

Case Scenario

End Points in PAH Clinical Trials

REVEAL Registry for PAH

REVEAL Registry Predictive Value of Clinical Worsening Definition

Prevention of Clinical Worsening

REVEAL Treatment at Time of Death

FREEDOM Trials Oral Treprostinil

GRIPHON Selexipag Reduces Morbidity and Mortality in PAH

Conclusions

Conclusions

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)