Improved outcome of treating locally advanced lung cancer with the use of Lattice Radiotherapy (LRT): A case report Beatriz E. Amendola, Naipy C. Perez,

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Improved outcome of treating locally advanced lung cancer with the use of Lattice Radiotherapy (LRT): A case report Beatriz E. Amendola, Naipy C. Perez, Xiaodong Wu, Jesus Manuel Blanco Suarez, Jiade J. Lu, Marco Amendola Clinical and Translational Radiation Oncology Volume 9, Pages 68-71 (February 2018) DOI: 10.1016/j.ctro.2018.01.003 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 Treatment plan of the LRT fraction showing color wash dose distribution of 3 Gy in the periphery and 18 Gy in the three lattice vertices of 1.5 cm diameter. Clinical and Translational Radiation Oncology 2018 9, 68-71DOI: (10.1016/j.ctro.2018.01.003) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 Top: CT-simulation showing a GTV of 218 cc equivalent to a 7.5 cm sphere diameter. Middle: CBCT demonstrating that volume of the lesion has decreased over 50% after 15 fractions. Bottom: CBCT on the last day of treatment. Clinical and Translational Radiation Oncology 2018 9, 68-71DOI: (10.1016/j.ctro.2018.01.003) Copyright © 2018 The Authors Terms and Conditions

Fig. 3 A: Initial FDG PET-CT showing metabolically active lesion in the left lung. B, C, D and E: serial follow up PET-CT images after 3, 9, 15, and 60 months of treatment completion with only minor post-radiation changes in the chest CT showing excellent response to treatment. Clinical and Translational Radiation Oncology 2018 9, 68-71DOI: (10.1016/j.ctro.2018.01.003) Copyright © 2018 The Authors Terms and Conditions