DNA Replication Essential Question: How do enzymes help ensure DNA is copied correctly?

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Presentation transcript:

DNA Replication Essential Question: How do enzymes help ensure DNA is copied correctly?

Why does DNA replicate? Cells copy genetic information before cell division so that each new cell has a complete set of DNA DNA replication occurs in the nucleus…WHY??

DNA Template

How does DNA replicate 1) UNWIND: Topoisomerase unwinds the coiled strands of DNA

2) UNZIP: DNA Helicase “unzips” the strands of DNA breaking the hydrogen bonds

3) HOLD OPEN: Single-Strand Binding proteins (SSBs) keep strands separated

4) BASE PAIRING: DNA polymerase III bonds free floating nucleotides with nucleotides from the parent strand using base pairing rules

6) PROOFREAD: DNA Polymerase I proofreads new strand and backtracks to correct errors

5) JOINING NUCLEOTIDES: DNA ligase bonds those nucleotides together.

The result is 2 identical DNA molecules.

Each w/1 new strand & 1 old strand Called Semi-conservative replication

(Continuous Replication) (Place where replication begins) (Replication starts & stops)

DNA Replication Animation

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