Christian Grommes, Anas Younes Cancer Cell

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Presentation transcript:

Ibrutinib in PCNSL: The Curious Cases of Clinical Responses and Aspergillosis Christian Grommes, Anas Younes Cancer Cell Volume 31, Issue 6, Pages 731-733 (June 2017) DOI: 10.1016/j.ccell.2017.05.004 Copyright © 2017 Terms and Conditions

Figure 1 Therapeutic Targeting of BTK in PCNSL (A) Activity of single-agent ibrutinib in PCNSL. (B) Ibrutinib inhibition of BTK in tumor cells induces favorable clinical responses, while inhibition of BTK in monocytes may lead to an increased incidence of invasive aspergillosis. Cancer Cell 2017 31, 731-733DOI: (10.1016/j.ccell.2017.05.004) Copyright © 2017 Terms and Conditions