Reopro removal during cardiopulmonary bypass using a hemoconcentrator

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Presentation transcript:

Reopro removal during cardiopulmonary bypass using a hemoconcentrator Michael Poullis, FRCS, Richard Manning, BSc, Dorian Haskard, FRCP, Kenneth Taylor, FRCS The Journal of Thoracic and Cardiovascular Surgery Volume 117, Issue 5, Pages 1032-1034 (May 1999) DOI: 10.1016/S0022-5223(99)70392-2 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 A, Platelet aggregation over time, with ADP concentrations from 0.625 to 5 μmol/mL. B, Platelet aggregation over time, with ReoPro concentration from 1.25 to 10 μg/L. C, Platelet aggregation over time, with time after initiation of bypass (ADP 5 μmol/mL final concentration). It can be seen that effective inhibition of platelet aggregation, due to RepPro removal, in response to 5.0 μmol/mL ADP is lost by 30 minutes. The data shown above were obtained from experiments using saline solution as the pump prime. The results obtained by using blood as the pump prime were identical. The Journal of Thoracic and Cardiovascular Surgery 1999 117, 1032-1034DOI: (10.1016/S0022-5223(99)70392-2) Copyright © 1999 Mosby, Inc. Terms and Conditions