Cytologically malignant margins of wedge resected stage I non-small cell lung cancer  Noriyoshi Sawabata, MD, Akihide Matsumura, MD, Mitsunori Ohota, MD,

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Cytologically malignant margins of wedge resected stage I non-small cell lung cancer  Noriyoshi Sawabata, MD, Akihide Matsumura, MD, Mitsunori Ohota, MD, Hajime Maeda, MD, Hiroshi Hirano, MD, Katsuhiro Nakagawa, MD, Hikaru Matsuda, MD  The Annals of Thoracic Surgery  Volume 74, Issue 6, Pages 1953-1957 (December 2002) DOI: 10.1016/S0003-4975(02)03993-0

Fig 1 Cross-section of tumor and margin cytology. To measure the tumor diameter and margin distance, the sample was cross-sectioned at the section containing the maximum diameter of tumor (top). The margin of this sample revealed malignant positive cytology despite a margin distance of 10 millimeters (bottom). These samples are from case 2 in Table 2. The Annals of Thoracic Surgery 2002 74, 1953-1957DOI: (10.1016/S0003-4975(02)03993-0)

Fig 2 A case of margin relapse. This patient (case 1 in Table 2) underwent tumor excision for peripheral stage I squamous cell lung cancer (a) with a margin distance of 15 millimeters (b). The patient suffered from margin relapse (c) within 8 months of tumor excision. The Annals of Thoracic Surgery 2002 74, 1953-1957DOI: (10.1016/S0003-4975(02)03993-0)

Fig 3 Survival by the status of margin cytology. The negative histology group (n = 7) had a 63%, 5-year survival rate, and the positive cytology group (n = 8) had a 43%, 5-year survival rate (p = 0.3). The Annals of Thoracic Surgery 2002 74, 1953-1957DOI: (10.1016/S0003-4975(02)03993-0)