Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials Carlos A. Cuello-Garcia, MD, Jan L. Brożek,

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Presentation transcript:

Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials Carlos A. Cuello-Garcia, MD, Jan L. Brożek, MD, PhD, Alessandro Fiocchi, MD, Ruby Pawankar, MD, Juan José Yepes-Nuñez, MD, MSc(Epi), Luigi Terracciano, MD, Shreyas Gandhi, BHSc, Arnav Agarwal, BHSc, Yuan Zhang, MD, Holger J. Schünemann, MD, MSc, PhD Journal of Allergy and Clinical Immunology Volume 136, Issue 4, Pages 952-961 (October 2015) DOI: 10.1016/j.jaci.2015.04.031 Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Study flow diagram. Journal of Allergy and Clinical Immunology 2015 136, 952-961DOI: (10.1016/j.jaci.2015.04.031) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Studies included in relation to the period/population when the intervention (probiotic) was administered (shaded areas). Direct evidence is displayed in boxes 1-3, when the probiotic was given to pregnant women, breast-feeding mothers, or infants. Indirect evidence is displayed in boxes 4-7, when probiotics were offered to any of the 3 possible populations. Journal of Allergy and Clinical Immunology 2015 136, 952-961DOI: (10.1016/j.jaci.2015.04.031) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions