Urine lipoarabinomannan testing for diagnosis of pulmonary tuberculosis in children: a prospective study Prof Mark P Nicol, PhD, Veronica Allen, MSc,

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Urine lipoarabinomannan testing for diagnosis of pulmonary tuberculosis in children: a prospective study Prof Mark P Nicol, PhD, Veronica Allen, MSc, Lesley Workman, MPH, Washiefa Isaacs, MSc, Jacinta Munro, Sandra Pienaar, MSc, Faye Black, MBBCh, Layla Adonis, MSc, Widaad Zemanay, PhD, Yonas Ghebrekristos, BSc, Prof Heather J Zar, PhD The Lancet Global Health Volume 2, Issue 5, Pages e278-e284 (May 2014) DOI: 10.1016/S2214-109X(14)70195-0 Copyright © 2014 Nicol et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 Study profile The Lancet Global Health 2014 2, e278-e284DOI: (10.1016/S2214-109X(14)70195-0) Copyright © 2014 Nicol et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Receiver operating characteristic curve for lipoarabinomannan lateral flow assay with different band intensities (stratified by HIV status), with mycobacterial culture as the reference standard ROC=receiver operating characteristic. The Lancet Global Health 2014 2, e278-e284DOI: (10.1016/S2214-109X(14)70195-0) Copyright © 2014 Nicol et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 3 Children with a positive ELISA test, by lateral flow assay band intensity p<0·0001, test for trend. The Lancet Global Health 2014 2, e278-e284DOI: (10.1016/S2214-109X(14)70195-0) Copyright © 2014 Nicol et al. Open Access article distributed under the terms of CC BY Terms and Conditions