Increased Cardiometabolic Traits in Pediatric Survivors of Acute Lymphoblastic Leukemia Treated with Total Body Irradiation Eric J. Chow, Jill H. Simmons,

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Presentation transcript:

Increased Cardiometabolic Traits in Pediatric Survivors of Acute Lymphoblastic Leukemia Treated with Total Body Irradiation Eric J. Chow, Jill H. Simmons, Christian L. Roth, K. Scott Baker, Paul A. Hoffmeister, Jean E. Sanders, Debra L. Friedman Biology of Blood and Marrow Transplantation Volume 16, Issue 12, Pages 1674-1681 (December 2010) DOI: 10.1016/j.bbmt.2010.05.016 Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Distribution of selected biomarkers stratified by HCT status: adiponectin, leptin, CRP, sICAM, sVCAM, and E-selectin. Boxes show median values and interquartile ranges, with whiskers denoting upper and lower adjacent values; outside values are denoted by closed circles. Differences between HCT survivors and non-HCT survivors were significant for adiponectin and CRP (P < .001 and P = .02, respectively); the distributions of other biomarkers were not significantly different in unadjusted analyses (leptin, P = .08; sICAM, P = .17; sVCAM, P = .96; E-selectin, P = .19). Biology of Blood and Marrow Transplantation 2010 16, 1674-1681DOI: (10.1016/j.bbmt.2010.05.016) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions