Current Status of Endoscopic Ultrasound Guided Ablation Techniques Jennifer Chennat  Gastroenterology  Volume 140, Issue 5, Pages 1403-1409 (May 2011) DOI: 10.1053/j.gastro.2011.03.003 Copyright © 2011 AGA Institute Terms and Conditions

Figure 1 (A) MRI/EUS before and (B) after EUS-guided ethanol lavagae of a small mucinous cystic lesion with atypical cytology results and cyst fluid CEA (500 ng/mL). Surgical resection of the post-lavaged cyst was performed and demonstrated a benign lesion with partially ablated cyst epithelium. (C) (bottom left) Diff-Quick stain, 200×. (D) (bottom right): H&E stain, 20×. (Figures are reprinted with permission of DeWitt J et al. Gastrointestinal Endoscopy 2009;70:710–723). Gastroenterology 2011 140, 1403-1409DOI: (10.1053/j.gastro.2011.03.003) Copyright © 2011 AGA Institute Terms and Conditions

Figure 2 (A) Iodine-25 brachytherapy seeds. (B) EUS-guided delivery of brachytherapy seeds. (C) Gold flexible fiducial. (D) Radiographic image demonstrating localized and concentrated fiducial placement after. (Figures A&B are reprinted with permission of Jin et al. Endoscopy 2008;40:314–320.) (Figures C & D are reprinted with permission of DiMaio et al, Gastrointestinal Endoscopy, 2010;71:1204–1210.) Gastroenterology 2011 140, 1403-1409DOI: (10.1053/j.gastro.2011.03.003) Copyright © 2011 AGA Institute Terms and Conditions

Figure 3 (A) Endoscopic ultrasound-guided device-based pancreatic tumor ablation. (B) Gross pathologic specimen, demonstrates a firm, beige 1.0 cm area corresponding to the treatment site. (C) Histopathology specimen: (H&E, orig. mag. 64×) 48 hours after RFA demonstrates a sharp demarcation between coagulated (C) and untreated pancreas (P). A 1 to 2 mm watershed zone of an early inflammatory response (I) surrounds the coagulated tissue. (Figures B & C are reprinted with permission of Goldberg et al. Gastrointestinal Endoscopy. 1999;50:392–401). Gastroenterology 2011 140, 1403-1409DOI: (10.1053/j.gastro.2011.03.003) Copyright © 2011 AGA Institute Terms and Conditions