FIGURE 1 Schematic of stable-isotope infusion studies performed for the measurement of BCAA and FFA kinetics. In study protocol 1, BCAA kinetics in 14.

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FIGURE 1 Schematic of stable-isotope infusion studies performed for the measurement of BCAA and FFA kinetics. In study protocol 1, BCAA kinetics in 14 IS and 12 IR subjects were measured with the use of [U-<sup>13</sup>C<sub>6</sub>]leucine and body composition measured with <sup>2</sup>H<sub>2</sub>O. [U-<sup>13</sup>C<sub>16</sub>]Palmitate was used in protocol 2 to quantify FFA kinetics in 13 IS and 12 IR subjects. Breath and blood samples were taken at intervals for the measurement of isotopic infusion at baseline and after infusion. Indirect calorimetry was performed for measurement of carbon dioxide excretion. BCAA, branched-chain amino acid; FFA, free fatty acid; IR, insulin-resistant; IS, insulin-sensitive; IV, intravenous, PO, oral administration. From: Alterations in branched-chain amino acid kinetics in nonobese but insulin-resistant Asian men Am J Clin Nutr. Published online October 24, 2018. doi:10.1093/ajcn/nqy208 Am J Clin Nutr | © 2018 American Society for Nutrition.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) 1