HISTOLOGY OF CARDIAC MUSCLE & HEART

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Presentation transcript:

HISTOLOGY OF CARDIAC MUSCLE & HEART

CIRCULATORY SYSTEM COMPONENTS BLOOD VASCULAR SYSTEM LYMPH VASCULAR SYSTEM COMPONENTS HEART ARTERIES CAPILLARIES VEINS LYMPHATIC CAPILLARIES LYMPH VESSELS LYMPHOID ORGANS

General Plan of Vessels Endothelium (Tunica Intima) Muscular tissue (Tunica Media) Connective tissue (Tunica Adventitia)

HEART Modified blood vessel ENDOCARDIUM: Simple squamous epithelium Sub endothelial connective tissue Sub endocardial connective tissue ( veins, purkinje fibers, arteries) Valves MYOCARDIUM: Thickest layer of cardiac muscles Arrangement EPICARDIUM: Loose connective tissue ( veins, nerves, ganglia) Mesothelium (visceral pericardium)

Heart Valves

CARDIAC MUSCLE

Cardiac Muscle

Atrial Muscle

Ischemia Regenerative capability Mesenchymal stem cell potential

INTERCALATED DISCS Junctional complexes at interface of adjacent cells Step like appearance Transverse portion Vertical portion Junctional specializations Fascia adherentes: (anchoring sites for actin) Macula adherentes: (desmosomes) Gap junctiona: in lateral portion

T- TUBULES & SARCOPLASMIC RETICULUM Less regular arrangement T- Tubules are more numerous At level of Z- line DIAD CONDUCTING SYSTEM Mitochondria more numerous Lipofuscin pigment granules

CARDIAC FIBROUS SKELETON Septum membranaceum Trigona fibrosa Annuli fibrosa Composed of dense connective tissue CONDUCTING SYSTEM