To be successful today… 1) Pull out scissors, glue & biology notebook
Mutations
Any mistake or change in DNA sequence Mutations Any mistake or change in DNA sequence What causes them? Random or Environment influences – X-rays, UV rays, radioactive materials, chemicals
Mutations Mutations can happen in body (somatic) cells or sex cells (gametes)
More about mutations Can be beneficial, harmless, or harmful 2 types: Gene & Chromosomal
Chromosomal mutation: affects whole or part of a chromosome Gene mutation: Changes to the bases in the DNA of ONE gene
1. Gene Mutations Change in one or more nucleotides Affects the amino acids and protein 2 types
Point Mutation (Substitution) Change in a single base pair in DNA Ex: The dog bit the CAT The dog bit the CAR
Sickle Cell Anemia
Frameshift Mutation Single base is added or deleted from DNA Changes the reading frame of the mRNA (the groups of 3).
Frameshift Mutation Alters every amino acid after insertion or deletion
Practice - Which mutations are these? 1 2 4 3 6 5
Gene Mutations Video