Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case- control study from Denmark Sidsel Arnspang Pedersen, MD, David Gaist,

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Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case- control study from Denmark Sidsel Arnspang Pedersen, MD, David Gaist, PhD, Sigrun Alba Johannesdottir Schmidt, PhD, Lisbet Rosenkrantz Hölmich, DMSc, Søren Friis, MD, Anton Pottegård, PhD Journal of the American Academy of Dermatology Volume 78, Issue 4, Pages 673-681.e9 (April 2018) DOI: 10.1016/j.jaad.2017.11.042 Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Flowchart of case selection. ∗Azathioprine, cyclosporine, and mycophenolate mofetil. BCC, Basal cell carcinoma; NMSC, nonmelanoma skin cancer; SCC, squamous cell carcinoma. Journal of the American Academy of Dermatology 2018 78, 673-681.e9DOI: (10.1016/j.jaad.2017.11.042) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Dose-response pattern between cumulative hydrochlorothiazide dose and risk of basal cell carcinoma (A) and squamous cell carcinoma (B). Error bars represent 95% confidence intervals. Journal of the American Academy of Dermatology 2018 78, 673-681.e9DOI: (10.1016/j.jaad.2017.11.042) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions