This month in Gastroenterology

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Presentation transcript:

This month in Gastroenterology Joseph H Sellin  Gastroenterology  Volume 125, Issue 6, Pages 1569-1570 (December 2003) DOI: 10.1053/j.gastro.2003.10.072

Figure 1 Photograph of ultrathin and conventional endoscopes. Gastroenterology 2003 125, 1569-1570DOI: (10.1053/j.gastro.2003.10.072)

Figure 2 CagA seroprevalence in H. pylori-infected populations of 13 studies. Gastroenterology 2003 125, 1569-1570DOI: (10.1053/j.gastro.2003.10.072)

Figure 3 Histology of colonic cross-sections at week 8 from models 2 and 3. Percent of animals harboring mild, moderate, and severe inflammation and fibrosis are shown as bar graphs representative of histology sections of (A) saline-treated, (B) TNBS-treated, TNBS plus NF-κB p65 antisense-treated (model 2) mice in which the (C) antisense or the (D) control oligonucleotide treatment was given 1 day before every TNBS treatment for 6 weeks, and TNBS + the (E) antisense or (F) control oligonucleotide given on weeks 5 and 6. Note increased trichrome-positive connective tissue in the submucosa of (B) TNBS mice and those given (D and F) TNBS and control oligonucleotide. Model 2 with the NF-κB antisense oligonucleotide given as a prophylaxis shows (C) complete lack of connective tissue build-up in contrast to (E) a mild increase in submucosal connective tissue in the therapeutic model 3. Gastroenterology 2003 125, 1569-1570DOI: (10.1053/j.gastro.2003.10.072)