Frequency of JAK1 and JAK2 alterations and their association with overall survival in TCGA datasets. Frequency of JAK1 and JAK2 alterations and their association.

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Frequency of JAK1 and JAK2 alterations and their association with overall survival in TCGA datasets. Frequency of JAK1 and JAK2 alterations and their association with overall survival in TCGA datasets. Kaplan–Meier survival analysis of TCGA skin cutaneous melanoma (A), breast invasive carcinoma (B), and prostate adenocarcinoma (C) provisional datasets, comparing control patients (blue) and patients harboring specified alterations in JAK1 and JAK2 (red). Frequency and distribution of combined JAK1 and JAK2 alterations are shown within each set of Kaplan–Meier plots. Significance testing of overall survival was performed using log-rank analysis. Daniel Sanghoon Shin et al. Cancer Discov 2017;7:188-201 ©2017 by American Association for Cancer Research