Primary Cardiac T-Cell Lymphoma Localized in the Mitral Valve

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Primary Cardiac T-Cell Lymphoma Localized in the Mitral Valve Yuma Motomatsu, MD, Yasuhisa Oishi, MD, PhD, Shogo Matsunaga, MD, Hirofumi Onitsuka, MD, Hidetaka Yamamoto, MD, PhD, Eiko Zaitsu, MD, Yuichi Yamada, MD, Kenichi Kohashi, MD, PhD, Yoshinao Oda, MD, PhD, Ryuji Tominaga, MD, PhD The Annals of Thoracic Surgery Volume 101, Issue 6, Pages 2363-2365 (June 2016) DOI: 10.1016/j.athoracsur.2015.08.091 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (Left) Preoperative transthoracic echocardiography shows that both leaflets of the mitral valve are hypertrophic and prolapsed (white arrows). (Right) Severe mitral regurgitation can be seen. The Annals of Thoracic Surgery 2016 101, 2363-2365DOI: (10.1016/j.athoracsur.2015.08.091) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Operative findings show a hypertrophic mitral valve and adhesion of the commissures. The Annals of Thoracic Surgery 2016 101, 2363-2365DOI: (10.1016/j.athoracsur.2015.08.091) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A) Section showing the mitral valve with proliferation of small- to medium-sized atypical lymphoid cells, accompanied by aggregates of epithelioid histiocytes (hematoxylin and eosin, ×400). Immunohistochemically, these atypical lymphoid cells were positive for (B) CD3, (C) CD4, and (D) CD8 (immunohistochemically staining, B ×400; C ×200; D ×200). The Annals of Thoracic Surgery 2016 101, 2363-2365DOI: (10.1016/j.athoracsur.2015.08.091) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions